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Sisodia, Sangram S.
One or more keywords matched the following items that are connected to Sisodia, Sangram S.
Item TypeName
Concept Protein Structure, Tertiary
Academic Article Defective neurite extension is caused by a mutation in amyloid beta/A4 (A beta) protein precursor found in familial Alzheimer's disease.
Academic Article Protein topology of presenilin 1.
Academic Article Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease.
Academic Article Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein.
Academic Article Familial Alzheimer disease-linked presenilin 1 variants enhance production of both Abeta 1-40 and Abeta 1-42 peptides that are only partially sensitive to a potent aspartyl protease transition state inhibitor of "gamma-secretase".
Academic Article Presenilin-dependent "gamma-secretase" processing of deleted in colorectal cancer (DCC).
Academic Article Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway.
Academic Article Presenilin-1-dependent transcriptome changes.
Academic Article P75 neurotrophin receptor regulates expression of neural cell adhesion molecule 1.
Academic Article Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of ?-secretase using synthetic antibodies.
Academic Article Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE.
Academic Article A synthetic antibody fragment targeting nicastrin affects assembly and trafficking of ?-secretase.
Academic Article The topology of pen-2, a ?-secretase subunit, revisited: evidence for a reentrant loop and a single pass transmembrane domain.
Academic Article Evidence That the "Lid" Domain of Nicastrin Is Not Essential for Regulating ?-Secretase Activity.
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  • Protein Structure Tertiary